In vivo intraoral reflectance confocal microscopy of an amalgam tattoo
Keywords:
reflectance confocal microscopy, amalgam tattoo, intraoral, melanomaAbstract
The majority of oral pigmentations are benign lesions such as nevi, melanotic macules, melanoacanthomas or amalgam tattoos. Conversely, mucosal melanomas are rare but often lethal; therefore, excluding oral melanomas in this setting is crucial. Reflectance confocal microscopy is a non-invasive in vivo imaging system with cellular resolution that has been used to distinguish benign from malignant pigmented lesions in the skin and more recently in the mucosae. However, lesions located posteriorly in the oral cavity are difficult to visually assess and biopsy due to their location. Herein we present a patient with multiple previous melanomas presenting with an oral amalgam tattoo in the buccal mucosa which was imaged using an intraoral telescopic probe attached to a commercially-available handheld RCM. In this case report we describe this novel probe, the first RCM description of an amalgam tattoo and we discuss its differences with the findings described in oral melanomas.
References
Maher NG, Solinas A, Scolyer RA, Guitera P. In vivo reflectance confocal microscopy for evaluating melanoma of the lip and its differential diagnoses. Oral Surg Oral Med Oral Pathol Oral Radiol. 2017;123(1):84-94. PMID: 27720652. 10.1016/j.oooo.2016.08.011
Lundin K, Schmidt G, Bonde C. Amalgam tattoo mimicking mucosal melanoma: a diagnostic dilemma revisited. Case Rep Dent. 2013;2013:787294. PMID: 23533829. D.O.I: 10.1155/2013/787294
Pellacani G, Guitera P, Longo C, Avramidis M, Seidenari S, Menzies S. The Impact of In Vivo Reflectance Confocal Microscopy for the Diagnostic Accuracy of Melanoma and Equivocal Melanocytic Lesions. J Invest Dermatol. 2007;127(12):2759-2765. PMID: D.O.I: http://dx.doi.org/10.1038/sj.jid.5700993
Peterson G, Zanoni DK, Migliacci J, Cordova M, Rajadhyaksha M, Patel S. Progress in reflectance confocal microscopy for imaging oral tissues in vivo. Proceedings of SPIE Photonics West 2016;9689.
Kose K, Cordova M, Duffy M, Flores ES, Brooks DH, Rajadhyaksha M. Video-mosaicing of reflectance confocal images for examination of extended areas of skin in vivo. Br J Dermatol. 2014;171(5):1239-1241. PMID: 24720744. D.O.I: 10.1111/bjd.13050
Debarbieux S, Perrot JL, Erfan N, et al. Reflectance confocal microscopy of mucosal pigmented macules: a review of 56 cases including 10 macular melanomas. Br J Dermatol. 2014;170(6):1276-1284. PMID: 24359328. D.O.I: 10.1111/bjd.12803
Uribe P, Collgros H, Scolyer RA, Menzies SW, Guitera P. In Vivo Reflectance Confocal Microscopy for the Diagnosis of Melanoma and Melanotic Macules of the Lip. JAMA Dermatol. 2017. PMID: 28467525. D.O.I: 10.1001/jamadermatol.2017.0504
Hashemi P, Pulitzer MP, Scope A, Kovalyshyn I, Halpern AC, Marghoob AA. Langerhans cells and melanocytes share similar morphologic features under in vivo reflectance confocal microscopy: a challenge for melanoma diagnosis. J Am Acad Dermatol. 2012;66(3):452-462. PMID: 21798622. D.O.I: 10.1016/j.jaad.2011.02.033
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