EMA-Positive Superficial ALK–Rearranged Myxoid Spindle Cell Neoplasm (SAMS): A Case Report of a Rare Entity and Dermoscopic Findings

EMA-Positive Superficial ALK–Rearranged Myxoid Spindle Cell Neoplasm (SAMS): A Case Report of a Rare Entity and Dermoscopic Findings

Authors

  • Gianluca Cafasso Oncologic Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria of Bologna, Bologna, Italy https://orcid.org/0009-0000-9366-7813
  • Carlotta Baraldi Oncologic Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria of Bologna, Bologna, Italy
  • Cosimo Misciali Oncologic Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria of Bologna, Bologna, Italy
  • Emi Dika Oncologic Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria of Bologna, Bologna, Italy
  • Barbara Corti Pathology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola-Malpighi, Bologna, Italy.

Keywords:

Anaplastic lymphoma kinase , Superficial myxoid spindle cell neoplasms ALK-rearranged neoplasms , Dermoscopy, Rare soft tissue

References

Dermawan JK, Azzato EM, Goldblum JR, et al. Superficial ALK-rearranged myxoid spindle cell neoplasm. Mod Pathol. 2021;34(9):1710-1718. DOI:10.1038/s41379-021-00830-w. PMID: 34088997

Luo W, Zheng J, Hei M, et al. Superficial ALK-rearranged myxoid spindle cell neoplasms. Ann Diagn Pathol. 2025;74:152395. DOI: 10.1016/j.anndiagpath.2024.152395 DOI:10.1016/j.anndiagpath.2024.152395. PMID: 38278264. PMID: 39550857

Hegazy S, Naous R. EMA-positive superficial ALK-rearranged myxoid spindle cell neoplasm. Am J Dermatopathol. 2024. DOI:10.1097/DAD.0000000000002734. PMID: 39150182

Kao YC, Sung YS, Zhang L, et al. Soft tissue tumors with kinase fusions. Genes Chromosomes Cancer. 2020;59(10):575-583. DOI:10.1002/gcc.22877. PMID: 32506523

Kelati A, Aqil N, Baybay H, et al. Dermoscopic patterns of dermatofibromas. J Med Case Rep. 2017;11(1):266. DOI:10.1186/s13256-017-1429-6. PMID: 28927449

Micantonio T, Gulia A, Altobelli E, et al. Vascular patterns in basal cell carcinoma. J Eur Acad Dermatol Venereol. 2011;25(3):358-361. DOI:10.1111/j.1468-3083.2010.03734.x. PMID:20561131.

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Published

2026-01-30

Issue

Vol. 16 No. 1 (2026): 2026 Vol 16, No 1 | January

Section

Research Letter

License

Copyright (c) 2026 Gianluca Cafasso, Carlotta Baraldi, Cosimo Misciali, Emi Dika, Barbara Corti

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Dermatology Practical & Conceptual applies a Creative Commons Attribution License (CCAL) to all works we publish (http://creativecommons.org/licenses/by-nc/4.0/). Authors retain the copyright for their published work.

How to Cite

1.
Cafasso G, Baraldi C, Misciali C, Dika E, Corti B. EMA-Positive Superficial ALK–Rearranged Myxoid Spindle Cell Neoplasm (SAMS): A Case Report of a Rare Entity and Dermoscopic Findings. Dermatol Pract Concept. 2026;16(1):6453. doi:10.5826/dpc.1601a6453

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